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1. Hepatitis B vaccine (HepB). (Minimum age: Birth)
At birth:
Administer
monovalent HepB to all newborns prior to hospital discharge.
If mother is HBsAg-positive,
administer HepB and 0.5 mL of hepatitis B immune globulin (HBIG) within 12
hours
of birth.
If mother's HBsAg status
is unknown, administer HepB within 12 hours of birth. Determine the
HBsAg status as
soon as possible and if HbsAg-positive,
administer HBIG (no later than age 1 week).
If mother is HBsAg-negative, the birth
dose can only be delayed with physician's order and mother's negative
HBsAg laboratory report documented in
the infant's medical record.
Following the birth dose:
The HepB series should be completed with
either monovalent HepB or a combination vaccine containing HepB.
The second dose should be
administered at age 1-2 months. The final dose should be administered
at age |
=>24 weeks. Infants born to HBsAg positive
mothers should be tested for HBsAg and antibody to HBsAg after
completion of
3 or more doses in a licensed HepB
series, at age 9-18 months (generally at the next well-child
visit).
4-month dose of HepB:
It is permissible to administer 4 doses of HepB when combination vaccines are given after the birth dose.
If monovalent HepB is used for doses after the
birth dose, a dose at age 4 months is not needed.
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